MRSA vaginitis: a clinical case of diagnostic and therapeutic challenge

Authors

  • Beatriz Câmara Médica Assistente de Medicina Geral e Familiar. Unidade de Saúde da Ilha de São Miguel. Ponta Delgada, Açores, Portugal.
  • Carmen Comino Médica Interna de Medicina Geral e Familiar. USF das Conchas, ULS Santa Maria. Lisboa, Portugal.
  • Ana Ventura Médica Assistente de Medicina Geral e Familiar. Unidade de Saúde da Ilha de São Miguel. Ponta Delgada, Açores, Portugal.
  • Ana Magalhães Médica Assistente Graduada de Medicina Geral e Familiar. USF das Conchas, ULS Santa Maria. Lisboa, Portugal.

DOI:

https://doi.org/10.32385/rpmgf.v41i6.14151

Keywords:

MRSA, Staphylococcus aureus, Vaginitis, Vulvovaginitis, Case report

Abstract

Introduction: Vaginitis, a vaginal infection commonly caused by bacteria, fungi, or viruses, poses increasing challenges due to colonization by multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA).

Case description: An 18-year-old woman, with no relevant medical history, presenting with genital burning and pain associated with itching, erythema, and vulvar wound sensation, was seen in the emergency department and treated for candidiasis. Due to continued complaints, she seeks out her family doctor for re-evaluation and, after gynaecological observation, she is medicated with boric acid vaginal tablets for complicated vaginal candidiasis. For financial reasons, the patient did not undergo therapy, and at the re-evaluation appointment, her initial complaints persisted. Vaginal exudate was then analysed and revealed an MRSA infection, which resolved with trimethoprim/sulfamethoxazole.

Commentary: This clinical case highlights the complexity of diagnosing MRSA vaginitis, a rare infection that can be mistaken for more common causes of vulvovaginitis, leading to delays in appropriate treatment. It underscores the importance of considering less frequent diagnostic hypotheses in cases of therapeutic refractoriness, reinforcing the crucial role of microbiological examinations in identifying the causal agent and guiding therapy. Furthermore, the study emphasizes the need for a rigorous medical approach, including patient education on warning signs and the importance of follow-up appointments. The report demonstrates the impact of continuity of care in general and family medicine. It highlights the scarcity of literature on this pathology, stressing the value of publishing clinical cases to advance medical knowledge.

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References

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Published

2026-01-07

How to Cite

MRSA vaginitis: a clinical case of diagnostic and therapeutic challenge. (2026). Portuguese Journal of Family Medicine and General Practice, 41(6), 527-32. https://doi.org/10.32385/rpmgf.v41i6.14151

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