Medical decision in COPD: the evidence-based history

António Duarte-de-Araújo, Miguel Guimarães, Pedro Teixeira, Venceslau Hespanhol, Jaime Correia-de-Sousa

Resumo


Randomized controlled trials together with systematic reviews and meta-analyses have been the cornerstone of clinical research. Some studies, because of the size of the sample, the use of randomization and well-defined measurements, the participation of multiple institutions, or long-term follow-up, are able to give a significant level of evidence. We chronologically describe and comment on a group of trials on chronic obstructive pulmonary disease (COPD) that have significantly influenced the scientific and medical community in understanding and managing the disease in the first years of the XXI century. They contributed to the different versions of the GOLD strategy.


Palavras-chave


COPD; Evidence; Randomized controlled trials; Treatment; Outcomes

Texto Completo:

PDF (English)


DOI: http://dx.doi.org/10.32385/rpmgf.v37i3.12780

Apontadores

  • Não há apontadores.


Copyright (c) 2021 Revista Portuguesa de Medicina Geral e Familiar

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.