Medical decision in COPD: the evidence-based history

Authors

  • António Duarte-de-Araújo 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. 2. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal. 3. Respiratory Department, H. Sª Oliveira, Guimarães, Portugal. http://orcid.org/0000-0001-5811-3786
  • Miguel Guimarães Respiratory Department, Centro Hospitalar de Gaia/Espinho
  • Pedro Teixeira 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. 2. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
  • Venceslau Hespanhol 1.Respiratory Department, Centro Hospitalar de S. João, Porto, Portugal. 2. Faculty of Medicine (FMUP), University of Porto, Portugal.
  • Jaime Correia-de-Sousa 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. 2. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.

DOI:

https://doi.org/10.32385/rpmgf.v37i3.12780

Keywords:

COPD, Evidence, Randomized controlled trials, Treatment, Outcomes

Abstract

Randomized controlled trials together with systematic reviews and meta-analyses have been the cornerstone of clinical research. Some studies, because of the size of the sample, the use of randomization and well-defined measurements, the participation of multiple institutions, or long-term follow-up, are able to give a significant level of evidence. We chronologically describe and comment on a group of trials on chronic obstructive pulmonary disease (COPD) that have significantly influenced the scientific and medical community in understanding and managing the disease in the first years of the XXI century. They contributed to the different versions of the GOLD strategy.

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Author Biographies

  • António Duarte-de-Araújo, 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. 2. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal. 3. Respiratory Department, H. Sª Oliveira, Guimarães, Portugal.

    Pneumologista do hospital de Guimarães.

    Doutorando em medicina.

  • Miguel Guimarães, Respiratory Department, Centro Hospitalar de Gaia/Espinho
    Pneumologista do hospital de Gaia-Espinho
  • Pedro Teixeira, 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. 2. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
    Docente da Escola de Medicina, Universidade do Minho
  • Venceslau Hespanhol, 1.Respiratory Department, Centro Hospitalar de S. João, Porto, Portugal. 2. Faculty of Medicine (FMUP), University of Porto, Portugal.
    Diretor de serviço de pneumologia do hospital de S. João e Professor de pneumologia da faculdade de Medicina da Universidade do Porto
  • Jaime Correia-de-Sousa, 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. 2. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.

    Medico Especialista de Medicina Geral e Familiar.

    Docente da Escola de Medicina da Universidade do Minho

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Published

2021-07-02

Issue

Vol. 37 No. 3 (2021): Revista Portuguesa de Medicina Geral e Familiar

Section

Opinion and Debate

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How to Cite

Medical decision in COPD: the evidence-based history. (2021). Portuguese Journal of Family Medicine and General Practice, 37(3), 272-6. https://doi.org/10.32385/rpmgf.v37i3.12780