Benign migratory glossitis: a case report
DOI:
https://doi.org/10.32385/rpmgf.v40i2.13928Keywords:
Benign migratory glossitis, Geographic tongueAbstract
Background: Benign migratory glossitis can be easily confused with differential diagnoses that have a potential unfavorable prognosis if not identified in a timely manner – although it is a common finding in the general population, with an estimated prevalence of up to 3% in healthy individuals in the general population worldwide – being early recognition is important.
Case description: A 22-year-old man, with a personal history of generalized anxiety disorder and panic attacks, seeks an acute illness consultation in primary health care due to complaints of lesions on the upper face and lateral edges of the tongue with approximately two months of evolution with sensation burns with hot foods and with fluctuating evolution. The patient presented an extensive analytical study without relevant changes and on physical examination the changes in the buccal mucosa were visible. Having already been treated with oral antifungals without success and given the characteristic appearance, the diagnosis of benign migratory glossitis was made, and the patient was reassured.
Comment: Benign migratory glossitis (BMG) is a relatively common clinical entity in the healthy general population (prevalence of 1 to 3%), with a chronic inflammatory basis that affects the tongue and adjacent buccal mucosa, usually with a fluctuating and chronic evolution. Despite its benignity and generally being asymptomatic, the associated signs can be a significant cause of concern and anxiety in patients, contributing to a decrease in quality of life in the absence of reassurance from the attending physician.
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Shareef S, Ettefagh L. Geographic tongue. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2024 Jan [updated 2023 Jul 31]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554466/
Picciani BL, Domingos TA, Teixeira-Souza T, Santos VC, Gonzaga HF, Cardoso-Oliveira J, et al. Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review. An Bras Dermatol. 2016;91(4):410-21.
Pereira RP, Oliveira JM, Pauletto P, Munhoz EA, Guerra EN, Massignan C, et al. Worldwide prevalence of geographic tongue in adults: a systematic review and meta-analysis. Oral Dis. 2023;29(8):3091-100.
Sarruf MB, Quinelato V, Sarruf GJ, Oliveira HE, Calasans-Maia JA, Quinelato H, et al. Stress as worsening of the signs and symptoms of the geographic tongue during the COVID-19 pandemic: a pilot study. BMC Oral Health. 2022;22(1):565.
Alikhani M, Khalighinejad N, Ghalaiani P, Khaleghi MA, Askari E, Gorsky M. Immunologic and psychologic parameters associated with geographic tongue. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;118(1):68-71.
Miloğlu O, Göregen M, Akgül HM, Acemoğlu H. The prevalence and risk factors associated with benign migratory glossitis lesions in 7619 Turkish dental outpatients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(2):e29-33.
Picciani BL, Silva-Junior GO, Michalski-Santos B, Avelleira JC, Azulay DR, Pires FR, et al. Prevalence of oral manifestations in 203 patients with psoriasis. J Eur Acad Dermatol Venereol. 2011;25(12):1481-3.
Pennings I, Singh A, Huryn JM, Estilo CL. Geographic tongue associated with palbociclib therapy. Oral Oncol. 2022;132:106001.
Martínez-García M, Roman-Sainz J, Silvestre-Torner N, Tabbara Carrascosa S. Bevacizumab-induced geographic tongue. Dermatol Pract Concept. 2021;11(3):e2021043.
Gonzaga HF, Chaves MD, Gonzaga LH, Picciani BL, Jorge MA, Dias EP, et al. Environmental factors in benign migratory glossitis and psoriasis: retrospective study of the association of emotional stress and alcohol and tobacco consumption with benign migratory glossitis and cutaneous psoriasis. J Eur Acad Dermatol Venereol. 2015;29(3):533-6.
Gonzaga HF, Marcos EV, Santana FC, Jorge MA, Tomimori J. HLA alleles in Brazilian patients with fissured tongue. J Eur Acad Dermatol Venereol. 2013;27(2):e166-70.
Campos WG, Esteves CV, Fernandes LG, Domaneschi C, Lemos Jr CA. Treatment of symptomatic benign migratory glossitis: a systematic review. Clin Oral Investig. 2018;22(7):2487-93.
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