When it is more than flu: case report of a viral myositis
DOI:
https://doi.org/10.32385/rpmgf.v38i4.13318Keywords:
Influenza, Flu, MyositisAbstract
Background: Upper respiratory tract infections are one of the most common motives for acute consultation in primary health care in children. Regardless, less common diseases, such as myositis, should be considered.
Content: Our eight-year-old male was observed at our primary health care unit in November 2019 with a two-day evolving fever and cough with no findings in the physical examination – a viral upper respiratory tract infection was assumed and treatment with antipyretic drugs and oral hydration was indicated. Three days later he returned with the maintenance of his clinical status, regardless of treatment, with abnormal gait and bilateral pain in the gastrocnemius muscle. The neurological and osteoarticular physical examination had no abnormalities. Nevertheless, he was referred to the pediatric emergency department for further evaluation. The emergency department had no additional findings in the physical examination. Blood tests were performed, which revealed a creatine kinase of 7110U/L, myoglobin of 1935ng/mL, and aspartate aminotransferase of 191U/L, with no changes in renal function. He was then admitted for intravenous fluid therapy with suspected myositis. The nasopharyngeal aspirate culture was performed and tested positive for Influenza B virus – Influenza B myositis was the presumed diagnosis. Treatment with oseltamivir was done for four days with a good response. He was discharged after four days with an indication to increase oral hydration and rest.
Conclusion: One should look for rarer symptoms in flu-like presentations and increase accessibility for patient re-evaluation.
Downloads
References
Mackay MT, Kornberg AJ, Shield LK, Dennett X. Benign acute childhood myositis: laboratory and clinical features. Neurology. 1999;53(9):2127-31.
Chu EC, Yip AS. A rare presentation of benign acute childhood myositis. Clin Case Rep. 2019;7(3):461-4.
Mall S, Buchholz U, Tibussek D, Jurke A, der Heiden MA, Diedrich S, et al. A large outbreak of influenza B-associated benign acute childhood myositis in Germany, 2007/2008. Pediatr Infect Dis J. 2011;30(8):e142-6.
Koliou M, Hadjiloizou S, Ourani S, Demosthenous A, Hadjidemetriou A. A case of benign acute childhood myositis associated with influenza A (H1n1) virus infection. Clin Microbiol Infect. 2010;16(2):193-5.
Middleton PJ, Alexander RM, Szymanski MT. Severe myositis during recovery from influenza. Lancet. 1970;2(7672):533-5.
Farrell MK, Partin JC, Bove KE. Epidemic influenza myopathy in Cincinnati in 1977. J Pediatr. 1980;96(3 Pt 2):545-51.
Ruff RL, Secrist D. Viral studies in benign acute childhood myositis. Arch Neurol. 1982;39(5):261-3.
Munoz MF. Seasonal influenza in children: clinical features and diagnosis. UpToDate [Internet]; 2020 [updated 2021 Nov 5]. Available from: https://www.uptodate.com/contents/seasonal-influenza-in-children-clinical-features-and-diagnosis
Agyeman P, Duppenthaler A, Heininger U, Aebi C. Influenza-associated myositis in children. Infection. 2004;32(4):199-203.
Crennan JM, Van Scoy RE, McKenna CH, Smith TF. Echovirus polymyositis in patients with hypogammaglobulinemia: failure of high-dose intravenous gammaglobulin therapy and review of the literature. Am J Med. 1986;81(1):35-42.
Bhai S, Naddaf E, Dimachkie MM. Overview of viral myositis. UpToDate; 2019 [updated 2022 May 31]. Available from: https://www.uptodate.com/contents/overview-of-viral-myositis
Downloads
Published
Issue
Section
License
Copyright (c) 2022 Portuguese Journal of Family Medicine and General Practice

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The authors will assign to the RPMGF the sole right to publish and distribute the content of the manuscript specified in this declaration via physical, electronic, broadcasting or any other medium that may come into existence. They also grant the RPMGF the right to use and exploit this manuscript, in particular by assigning, selling or licensing its content. This permission is permanent and takes effect from the moment the manuscript is submitted, has the maximum duration allowed by applicable Portuguese or international law and is of worldwide scope. The authors further declare that this assignment is made free of charge. If the RPMGF informs the authors that it is not going to publish their manuscript, the exclusive assignment of rights ceases forthwith.
The authors authorise the RPMGF (or any entity it may appoint) to act on their behalf when it believes that copyright may have been infringed.