Spondyloarthritis and Crohn’s disease in an adolescent

Authors

  • Liliana Marto Médica de Família. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.
  • Tiago Baptista Médico de Família. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.
  • Renata Sousa Médica de Família. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.
  • Carla Martins Médica de Família. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.
  • Sara Araújo Médica de Família. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.
  • Ana Lúcia Cruz Médica de Família. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.
  • Ana Raquel Pinhão Médica Interna de Medicina Geral e Familiar. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.
  • Catarina Morais Médica Interna de Medicina Geral e Familiar. USF Tiago de Almeida, ULS do Alto Minho. Viana do Castelo, Portugal.

DOI:

https://doi.org/10.32385/rpmgf.v40i5.13970

Keywords:

Spondyloarthritis, Crohn's disease, Adalimumab

Abstract

Introduction: This case report follows an adolescent female with articular and bowel symptoms, highlighting the association between spondyloarthritis and Crohn’s disease.

Case description: The first symptoms were joint pain, mainly in the knee and lower back leading to a possible autoimmune disease diagnosis, supported by elevation of inflammatory markers and magnetic resonance imaging showing sacroilitis. After that, the patient developed diarrhea and rectal bleeding, with colonoscopy revealing pancolitis and ulcerations. Main diagnosis, therapeutics, and results: The initial evaluation by a rheumatology specialist suggested spondyloarthritis or juvenile idiopathic arthritis as differential diagnosis establishing treatment with non-steroidal anti-inflammatory drugs and prednisolone. Cooperation with gastroenterology led to the diagnosis of spondyloarthritis associated with Crohn’s disease, changing the medication to adalimumab.

Comment: This clinical case report highlights the importance of interdisciplinary cooperation when managing complex diagnoses and establishing suitable therapeutical strategies in autoimmune diseases. This case reinforces the role of the family doctor as a patient manager and as a key element in the acceptance of chronic illness by the patient and their family.

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References

1. Karreman MC, Luime JJ, Hazes JM, Weel AE. The prevalence and incidence of axial and peripheral spondyloarthritis in inflammatory bowel disease: a systematic review and meta-analysis. J Crohns Colitis. 2017;11(5):631-42.

2. Ranasinghe IR, Tian C, Hsu R. Crohn disease [Internet]. Treasure Island: StatPearls Publishing; 2023 Jan [updated 2024 Feb]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK436021/

3. Ossum AM, Palm Ø, Lunder AK, Cvancarova M, Banitalebi H, Negård A, et al. Ankylosing spondylitis and axial spondyloarthritis in patients with long-term inflammatory bowel disease: results from 20 years of follow-up in the IBSEN study. J Crohns Colitis. 2018;12(1):96-104.

4. Lim CS, Tremelling M, Hamilton L, Kim M, Macgregor A, Turmezei T, et al. Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study. Rheumatology (Oxford). 2023;62(4):1511-8.

5. Danve A, Deodhar A. Axial spondyloarthritis in the USA: diagnostic challenges and missed opportunities. Clin Rheumatol. 2019;38(3):625-34.

6. Peyrin-Biroulet L, Loftus EV Jr, Colombel JF, Sandborn WJ. Long-term complications, extraintestinal manifestations, and mortality in adult Crohn’s disease in population-based cohorts. Inflamm Bowel Dis. 2011;17(1):471-8.

7. Tromm A, May D, Almus E, Voigt E, Greving I, Schwegler U, et al. Cutaneous manifestations in inflammatory bowel disease. Z Gastroenterol. 2001;39(2):137-44.

8. Abdesslem NB, Mahjoub A, Sayadi S, Zbiba W. Ocular manifestations of Crohn’s disease. Tunis Med. 2019;97(5):692-7.

9. Youssef J, Novosad SA, Winthrop KL. Infection risk and safety of corticosteroid use. Rheum Dis Clin North Am. 2016;42(1):157-76.

10. Mokhtare M, Valizadeh SM, Emadian O. Lower gastrointestinal bleeding due to non-steroid anti-inflammatory drug-induced colopathy case report and literature review. Middle East J Dig Dis. 2013;5(2):107-11.

Published

2024-11-06

How to Cite

Spondyloarthritis and Crohn’s disease in an adolescent. (2024). Portuguese Journal of Family Medicine and General Practice, 40(5), 498-504. https://doi.org/10.32385/rpmgf.v40i5.13970

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