Hormone replacement therapy - The controversy

Abstract

A Hormone Replacement Therapy (HRT) with estrogen alone, or in combination with progestin, was, until recently, a preferred therapeutic in the prevention and treatment of many of the problems of climacteric. He got up, still, the hope of its effects in primary and even secondary cardiovascular disease. Recent studies have, however, lead to a more cautious, the use of these drugs. These suggest an increased risk of cardiovascular and breast cancer in women using HRT. These studies show, however, some limitations as important by many authors. On the other hand, increases the risk encountered, were smaller. Based on current knowledge, therefore continues to recommend itself, a careful evaluation of the risks and benefits of HRT for each woman, a sharing of decisions between doctor and patient and an annual reassessment of the situation. Should not be forgotten the alternatives therapeutic effects are well documented, such as aspirin, statins and control of hypertension, cardiovascular risk reduction, bisphosphonates, and others in the treatment of osteoporosis and other for other health problems climacteric.