Buschke-Löwenstein tumor: a (un)preventable case
DOI:
https://doi.org/10.32385/rpmgf.v39i5.12791Keywords:
Buschke-Löwenstein tumor, Papillomavirus infections, Women’s health, Preventive medicineAbstract
Introduction: Buschke-Löwenstein tumor is a rare tumor associated with human papillomavirus (HPV), most commonly HPV DNA types 6 and 11. This tumor can present an aggressive local invasive growth pattern with a high impact on quality of life. Early diagnosis and treatment of the condyloma acuminate can prevent this tumor development.
Case report: We present a 49-year-old female, married, who has had a general and family medicine follow-up at a private practice for several years. In June 2016, a family physician was assigned to her family in public services, and she started to attend urgent care. In January 2018, she arranged an urgent appointment with her family physician where she showed a vulvar and peri-anal lesion. On examination, there were two large verrucous, malodorous growth masses: one measuring 9x6cm in the vulvar region and 5x7.5cm in the peri-anal region. When asked, the patient revealed that a small vulvar lesion appeared in 1992 and a peri-anal lesion in 2015, but they had a massive growth since 2017. After the explanation of the possible disease, the patient was referred to a gynecology consultation in the referral hospital. Towards the diagnosis of Buschke-Löwenstein tumor, she was submitted to a radical surgical excision with a protective colostomy, followed by plastic reconstruction of the anovulvar region. After the surgery, the patient had difficulty accepting her body image, with a great impact on her mental health.
Comment: The follow-up at a women’s healthcare consultation, a specific consultation of general and family medicine specialty could permit an early identification of condyloma lesion and change the natural course of the disease, reducing physical and mental morbidity on the patient.
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References
Venter F, Heidari A, Viehweg M, Rivera M, Natarajan P, Cobos E. Giant condylomata acuminata of Buschke-Lowenstein associated with paraneoplastic hypercalcemia. J Investig Med High Impact Case Rep. 2018;6:2324709618758348.
Rosen T, Callen J, Ofori A. Condylomata acuminata (anogenital warts) in adults: epidemiology, pathogenesis, clinical features, and diagnosis. In: UpToDate [Internet]; 2022 Dec 21 [updated 2023 Sep]. Available from: https://www.uptodate.com/contents/condylomata-acuminata-anogenital-warts-in-adults-epidemiology-pathogenesis-clinical-features-and-diagnosis
Caldo D. Tumor de Burschke-Loewenstein na região perianal: um caso clínico [(Burschke-Loewenstein tumor in perianal region: clinical case]. Rev Port Cir. 2010;II(13):39-42. Portuguese
Lévy A, Lebbe C. Prise en charge des tumeurs de Buschke-Löwenstein [Buschke-Löwenstein tumour: diagnosis and treatment]. Ann Urol. 2006;40(3):175-8. French
American Psychiatric Association. Manual diagnóstico e estatístico de transtornos mentais - DSM-5. 5ª ed. Climepsi Editores; 2013. ISBN 9789727963478
Cabral AS, Paredes T. Distress e perturbações de adaptação. In: Albuquerque E, Cabral AS, editors. Psico-oncologia: temas fundamentais. Lidel; 2015. p. 195-204. ISBN 9789897521362
Renzi A, Giordano P, Renzi G, Landolfi V, Del Genio A, et al. Buschke-Lowenstein tumor successful treatment by surgical excision alone: a case report. Surg Innov. 2006;13(1):69-72.
Granja M. Rastreio oncológico: conceitos, orientações e práticas [Cancer screening: concepts, trends, and practices]. Acta Med Port. 2001;14(4):441-7. Portuguese
Lei no 48/90, de 24 de agosto. Diário da República. I Série;(195).
Botas P. Capacitação: uma ciência com arte [Enablement: a science with art]. Rev ADSO. 2013;1(1):13-6. Portuguese
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